Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 2/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.49 |
| ▸ | ITGAL | P20701 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 2/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816279 | 1.00 | ITGB2 (0.49) | ITGB2ICAM1ITGALLMNAFOLH1 | |
| SCHEMBL11694141 | 0.94 | LMNA (0.47) | ITGB2ICAM1ITGALLMNAFOLH1 | |
| SCHEMBL11692579 | 0.92 | ITGB2 (0.45) | ITGB2ICAM1ITGALLMNAFOLH1 | |
| SCHEMBL11692575 | 0.92 | ITGB2 (0.45) | ITGB2ICAM1ITGALLMNAFOLH1 | |
| SCHEMBL10879046 | 0.89 | LMNA (0.46) | ITGB2ICAM1ITGALLMNACA2 | |
| SCHEMBL9816278 | 0.89 | LMNA (0.46) | ITGB2ICAM1ITGALLMNACA2 | |
| SCHEMBL11012485 | 0.87 | CA2 (0.43) | ITGB2ICAM1ITGALLMNAFOLH1 | |
| SCHEMBL9816321 | 0.85 | LMNA (0.40) | ITGB2ICAM1ITGALLMNAFOLH1 | |
| SCHEMBL9816330 | 0.85 | SMN1; SMN2 (0.49) | LMNACA2CA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9816296 | 0.82 | ALDH1A1 (0.53) | LMNAFOLH1CA2CA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153992-B1 | WATER SOLUBLE DERIVATIVES OF 3,5-DIACETO AMIDO-2,4,6-TRIIODOBENZOIC ACID AND PROCESS FOR THEIR PREPARATION AND USE | Dr. Franz Köhler Chemie GmbH (DE) | 1991-10-16 | — | — | EP | disclosed |
| EP-0153992-A2 | Water soluble derivatives of 3,5-diaceto amido-2,4,6-triiodobenzoic acid and process for their preparation and use | Dr. Franz Köhler Chemie GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |