Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816569 | 0.86 | — | — | |
| SCHEMBL7839615 | 0.84 | APEX1 (0.43) | APEX1LTA4HS1PR1S1PR3S1PR5 | |
| SCHEMBL9816708 | 0.80 | RELA (0.33) | TSHR | |
| SCHEMBL10618138 | 0.80 | FNTA (0.42) | APEX1LTA4HS1PR1S1PR3S1PR5 | |
| SCHEMBL14742262 | 0.79 | APEX1 (0.39) | APEX1CAMK2ALTA4HGPR84FFAR1 | |
| SCHEMBL12540884 | 0.79 | LTA4H (0.40) | APEX1LTA4HS1PR1S1PR3S1PR5 | |
| SCHEMBL21012624 | 0.78 | CAMK2A (0.55) | CAMK2ALTA4HGPR84FFAR1FFAR4 | |
| SCHEMBL17822770 | 0.76 | GPR84 (0.56) | APEX1CAMK2AGPR84FFAR1FFAR4 | |
| SCHEMBL11696751 | 0.75 | APEX1 (0.79) | APEX1CAMK2AGPR84FFAR1FFAR4 | |
| SCHEMBL12935681 | 0.75 | PRMT1 (0.48) | CAMK2ALTA4HS1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174909-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1991-10-16 | — | — | EP | disclosed |
| EP-0141776-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1987-07-08 | — | — | EP | disclosed |
| EP-0076782-B1 | REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1986-03-05 | — | — | EP | disclosed |
| EP-0076782-A2 | Reactive dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1983-04-13 | — | — | EP | disclosed |
| EP-0074928-A2 | Reactive dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1983-03-23 | — | — | EP | disclosed |