Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | IAPP | P10997 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817281 | 0.83 | GPR35 (0.40) | GPR35ALDH1A1HTTHPGDMEN1 | |
| SCHEMBL9817271 | 0.77 | CYP4F2 (0.39) | IAPPMEN1KMT2APOLBMAPT | |
| SCHEMBL9817322 | 0.77 | CTSB (0.41) | GPR35ALDH1A1HTTCRHBPCRHR2 | |
| SCHEMBL9817264 | 0.75 | GPR35 (0.42) | GPR35ERN1ALDH1A1HTTCRHBP | |
| SCHEMBL9445177 | 0.75 | CYP4F2 (0.54) | GPR35ALDH1A1CRHBPCRHR2HPGD | |
| SCHEMBL9817211 | 0.73 | GPR35 (0.41) | GPR35ALDH1A1HTTHPGDMEN1 | |
| SCHEMBL9817303 | 0.69 | GPR35 (0.39) | GPR35ALDH1A1HPGDMEN1CYP3A4 | |
| SCHEMBL27864868 | 0.69 | GPR35 (0.53) | GPR35ERN1ALDH1A1CXCR1CXCR2 | |
| SCHEMBL5496520 | 0.68 | GPR35 (0.60) | GPR35ERN1ALDH1A1CRHBPCRHR2 | |
| SCHEMBL3290647 | 0.68 | ALDH1A1 (0.53) | ALDH1A1HTTHPGDMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248213-B1 | HYDROXYPHENYL- AND HYDROXYPHENOXYALKANOIC ACID IODOPROPARGYL ESTERS | THE DOW CHEMICAL COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-4731466-A | FUNGICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0248213-A2 | Hydroxyphenyl- and hydroxyphenoxyalkanoic acid iodopropargyl esters | THE DOW CHEMICAL COMPANY (US) | 1987-12-09 | — | — | EP | disclosed |