Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817696 | 0.97 | CYP4F2 (0.38) | CYP4F2CYP4A11FFAR1PTGER4CYP1A2 | |
| SCHEMBL9817771 | 0.94 | CYP4F2 (0.39) | CYP4F2CYP4A11FFAR1S1PR5FFAR4 | |
| SCHEMBL9817669 | 0.89 | CYP4F2 (0.43) | CYP4F2CYP4A11FAAHMGLLFFAR1 | |
| SCHEMBL9817664 | 0.89 | HPGD (0.35) | FFAR1CYP3A4S1PR5 | |
| SCHEMBL9817856 | 0.87 | CYP4Z1 (0.38) | CYP4F2CYP4A11FAAHMGLLFFAR1 | |
| SCHEMBL9817777 | 0.86 | PPARA (0.35) | CYP4F2CYP4A11FAAHMGLLFFAR1 | |
| SCHEMBL9817603 | 0.86 | CYP4F2 (0.40) | CYP4F2CYP4A11FFAR1PTGER4CYP1A2 | |
| SCHEMBL9817683 | 0.84 | CYP4Z1 (0.37) | CYP4F2CYP4A11FAAHMGLLFFAR1 | |
| SCHEMBL6665905 | 0.84 | CYP3A4 (0.37) | CYP4F2CYP4A11PTGER4CYP3A4SMN1; SMN2 | |
| SCHEMBL9817649 | 0.84 | ALOX5 (0.36) | CYP4F2CYP4A11FFAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290130-B1 | ACETYLENES DISUBSTITUTED WITH A PHENYL GROUP AND A HETEROBICYCLIC GROUP HAVING RETINOID LIKE ACTIVITY | ALLERGAN, INC (US) | 1991-11-06 | — | — | EP | disclosed |
| US-4810804-A | PSORIASIS | ALLERGAN, INC. (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0290130-A1 | Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid like activity | ALLERGAN, INC (US) | 1988-11-09 | — | — | EP | disclosed |