Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PPIB | P23284 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | PPIG | Q13427 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254038 | 0.91 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL17791311 | 0.85 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL92326 | 0.85 | MEN1 (0.53) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL16125663 | 0.85 | ALDH1A1 (0.46) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL15944747 | 0.85 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL24019226 | 0.85 | ALDH1A1 (0.46) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL4354853 | 0.84 | ALDH1A1 (0.44) | ALDH1A1LMNACYP3A4TSHRMEN1 | |
| SCHEMBL10720993 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TSHRMEN1KMT2ATHRB | |
| SCHEMBL9554958 | 0.84 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL148297 | 0.84 | MAOB (0.47) | ALDH1A1TSHRMAOBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169205-B1 | METHOD OF PREPARING COPOLYMERS UTILIZING ISOIMIDES | Hughes Aircraft Company (US) | 1991-11-13 | — | — | EP | disclosed |
| US-4613637-A | COATINGS, FILMS, ENCAPSULANTS | HUGHES AIRCRAFT COMPANY (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0169205-A1 | METHOD OF PREPARING COPOLYMERS UTILIZING ISOIMIDES. | HUGHES AIRCRAFT CO (US) | 1986-01-29 | — | — | EP | disclosed |
| WO-1985002853-A1 | COPOLYMERS UTILIZING ISOIMIDES AND METHOD OF PREPARING SAME | HUGHES AIRCRAFT COMPANY (US) | 1985-07-04 | — | — | WO | disclosed |