Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.69 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3656725 | 0.92 | CTSL (0.58) | CTSLSIRT2SLC1A3SLC1A1CTSS | |
| SCHEMBL7996588 | 0.91 | CTSL (0.57) | CTSLSIRT2SLC1A3SLC1A1CTSS | |
| SCHEMBL10419670 | 0.91 | CTSL (0.69) | CTSLSIRT2CTSSITGB3ITGA2B | |
| SCHEMBL7320626 | 0.86 | CTSL (0.57) | CTSLSIRT2SLC1A3SLC1A1CTSS | |
| SCHEMBL7792804 | 0.86 | CTSL (0.66) | CTSLSIRT2CTSSITGB3ITGA2B | |
| SCHEMBL7792802 | 0.86 | CTSL (0.66) | CTSLSIRT2CTSSITGB3ITGA2B | |
| Lysine SCHEMBL10720682 | 0.85 | ITGB3 (0.60) | CTSLSIRT2ITGB3ITGA2BSIRT1 | |
| SCHEMBL3251534 | 0.85 | CTSL (0.65) | CTSLSIRT2ITGB3ITGA2BSIRT1 | |
| SCHEMBL3251530 | 0.85 | CTSL (0.65) | CTSLSIRT2ITGB3ITGA2BSIRT1 | |
| SCHEMBL10421088 | 0.84 | FOLH1 (0.62) | CTSLSIRT2CTSSITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302799-B1 | PROCESS FOR THE PREPARATION OF L,L OR D,D OR RACEMIC N6-BENZYLOXYCARBONYL-2,6-DIAMINO-PIMELAMIC ACID | RHONE-POULENC SANTE (FR) | 1991-10-09 | — | — | EP | claimed |
| EP-0302799-A2 | Process for the preparation of L,L or D,D or racemic N6-benzyloxycarbonyl-2,6-diamino-pimelamic acid | RHONE-POULENC SANTE (FR) | 1989-02-08 | — | — | EP | disclosed |