Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469182 | 0.72 | MAPK14 (0.74) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL9158038 | 0.71 | DPP4 (0.44) | CYP1A2CYP3A4CYP2C9KDM4EHTT | |
| SCHEMBL9047925 | 0.69 | SCN2A (0.51) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL9047927 | 0.69 | SCN2A (0.51) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL9048174 | 0.68 | SCN2A (0.80) | SCN2A | |
| SCHEMBL4776816 | 0.68 | PIN1 (0.45) | MAPK14PIN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30096811 | 0.66 | CYP1A2 (0.53) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL4453854 | 0.66 | CTSS (0.46) | MAPK14PIN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2372504 | 0.66 | DHODH (0.69) | CYP1A2CYP3A4CYP2C9KDM4EHTT | |
| SCHEMBL6365406 | 0.66 | RAF1 (0.53) | MAPK14MAPK13MAPK12MAPK11RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3141267-A | — | — | None | — | — | JP | disclosed |
| JP-H03141267-A | 2,4-DIPHENYL-5-METHYLSULFONYLPYRIMIDINE DERIVATIVE AND PRODUCTION THEREOF | SUMITOMO CHEM CO LTD | 1991-06-17 | — | — | JP | disclosed |