Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.73 |
| ▸ | FABP4 | P15090 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | IL1RN | P18510 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.51 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487708 | 0.89 | WDR5 (0.73) | WDR5POLBMEN1KMT2APFKFB3 | |
| SCHEMBL9818397 | 0.89 | WDR5 (0.69) | WDR5POLBMEN1KMT2APFKFB3 | |
| SCHEMBL29534877 | 0.87 | WDR5 (0.72) | WDR5FABP4POLBMEN1KMT2A | |
| SCHEMBL24102933 | 0.87 | WDR5 (0.72) | WDR5FABP4POLBMEN1KMT2A | |
| SCHEMBL28543927 | 0.86 | KDM4E (0.59) | WDR5FABP4MEN1KMT2APGR | |
| SCHEMBL3789469 | 0.85 | KEAP1 (0.64) | WDR5MEN1KMT2APGRALDH1A1 | |
| SCHEMBL2444333 | 0.85 | KEAP1 (0.64) | WDR5MEN1KMT2APGRALDH1A1 | |
| SCHEMBL7365696 | 0.84 | KDM4E (0.64) | WDR5POLBMEN1KMT2APFKFB3 | |
| SCHEMBL29261787 | 0.83 | PFKFB3 (0.68) | WDR5POLBMEN1KMT2APFKFB3 | |
| SCHEMBL711356 | 0.82 | WDR5 (0.60) | WDR5POLBMEN1KMT2APFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989323-A | N- (cyclopropylmethyl) -5- (methylsulfonyl) -N- {1- [1- (pyrimidin-2-yl) -1H-1, 2, 4-triazol-5-yl ] ethyl } benzamide derivatives and corresponding picolinamide derivatives as pesticides | 拜耳公司 | 2020-11-24 | — | — | CN | disclosed |