Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818407 | 0.89 | GAA (0.56) | HTR6GAAKDM4EALDH1A1PKM | |
| SCHEMBL8143772 | 0.86 | HTR6 (0.52) | HTR6GAAKDM4EALDH1A1PKM | |
| SCHEMBL9818411 | 0.83 | APP (0.57) | GAAKDM4EALDH1A1PKMHPGD | |
| SCHEMBL10388597 | 0.82 | KDM4E (0.49) | GAAKDM4EALDH1A1PKML3MBTL1 | |
| SCHEMBL2487383 | 0.81 | ALDH1A1 (0.54) | HTR6GAAKDM4EALDH1A1HPGD | |
| SCHEMBL1162839 | 0.81 | HTR6 (0.66) | HTR6GAAKDM4EALDH1A1PKM | |
| SCHEMBL29480329 | 0.81 | HTR6 (0.66) | HTR6GAAKDM4EALDH1A1PKM | |
| SCHEMBL30513963 | 0.81 | ALDH1A1 (0.54) | HTR6GAAKDM4EALDH1A1HPGD | |
| SCHEMBL17774701 | 0.81 | HTR6 (0.69) | HTR6GAAKDM4EALDH1A1PKM | |
| SCHEMBL14189076 | 0.79 | POLB (0.54) | HTR6GAAKDM4EALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997921-A | Substituted phenylazosulfoindole dyes | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4954563-A | Polyamide dye | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0121495-B1 | MONOAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1986-12-17 | — | — | EP | disclosed |
| EP-0121495-A1 | Monoazo dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-10-10 | — | — | EP | disclosed |