Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143772 | 0.93 | HTR6 (0.52) | GAAALDH1A1KDM4ERAPGEF4KMT2A | |
| SCHEMBL9818411 | 0.90 | APP (0.57) | GAAALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL9818432 | 0.89 | HTR6 (0.61) | GAAALDH1A1KDM4EPOLBHTR6 | |
| SCHEMBL9722812 | 0.87 | CA2 (0.57) | GAAALDH1A1KDM4ERAPGEF4KMT2A | |
| SCHEMBL9299326 | 0.86 | ALDH1A1 (0.51) | GAAALDH1A1KDM4ERAPGEF4KMT2A | |
| SCHEMBL3278551 | 0.86 | POLB (0.51) | GAAALDH1A1KDM4ERAPGEF4KMT2A | |
| SCHEMBL10388597 | 0.82 | KDM4E (0.49) | GAAALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL9818408 | 0.82 | ALDH1A1 (0.55) | GAAALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL5261185 | 0.82 | BCHE (0.47) | GAAALDH1A1KDM4ERAPGEF4KMT2A | |
| SCHEMBL2004711 | 0.81 | HTR6 (0.71) | GAAALDH1A1KDM4ERAPGEF4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997921-A | Substituted phenylazosulfoindole dyes | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4954563-A | Polyamide dye | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0121495-B1 | MONOAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1986-12-17 | — | — | EP | disclosed |
| EP-0121495-A1 | Monoazo dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-10-10 | — | — | EP | disclosed |