Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.43 |
| ▸ | LOX | P28300 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | C1S | P09871 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389380 | 0.83 | LMNA (0.69) | LMNAMAPTLOXL2LOXMAOA | |
| SCHEMBL5258855 | 0.82 | HTR6 (0.61) | MAPTKIF18AL3MBTL1HTR6 | |
| SCHEMBL5261746 | 0.82 | MEN1 (0.57) | KIF18AHTR6CA1CA2CA9 | |
| SCHEMBL10388597 | 0.82 | KDM4E (0.49) | LMNAHTTCYP2A6KAT6ALOXL2 | |
| SCHEMBL10389258 | 0.82 | ALDH1A1 (0.54) | LMNALOXL2LOXMAOAF2 | |
| SCHEMBL4368038 | 0.79 | HSD11B1 (0.51) | LMNAKAT6ALOXL2LOXMAOA | |
| SCHEMBL13241564 | 0.79 | ALDH1A1 (0.61) | LMNAHTTCYP2A6KAT6ALOXL2 | |
| SCHEMBL10661698 | 0.78 | CYP3A4 (0.52) | MAPTKIF18ACA1CA2CA9 | |
| SCHEMBL3278551 | 0.76 | POLB (0.51) | MAPTKIF18A | |
| SCHEMBL10389253 | 0.76 | GAA (0.44) | LMNAKAT6AC1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997921-A | Substituted phenylazosulfoindole dyes | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4954563-A | Polyamide dye | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |