SCHEMBL981877

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10095715	0.92	PFKFB3 (0.42)	KITPFKFB3PFKFB1PFKFB2NSD2
	SCHEMBL980476	0.92	LMNA (0.46)	KITLMNAMAPTTP53KMT2A
	SCHEMBL10095321	0.89	MTNR1A (0.47)	KITPFKFB3PFKFB1PFKFB2NSD2
	SCHEMBL10096330	0.89	ESR1 (0.47)	ESR1
	SCHEMBL10096732	0.89	MAPT (0.45)	LMNAMAPTTP53KMT2AALDH1A1
	SCHEMBL10096386	0.89	KIT (0.38)	KITPFKFB3PFKFB1PFKFB2NSD2
	SCHEMBL10096243	0.89	KCNA5 (0.43)	LMNAMAPTALDH1A1ESR1
	SCHEMBL10096383	0.88	KIT (0.37)	KITPFKFB3PFKFB1PFKFB2NSD2
	SCHEMBL10096667	0.88	ESR1 (0.37)	KITPFKFB3PFKFB1PFKFB2NSD2
	SCHEMBL10096664	0.88	KCNA5 (0.44)	KITLMNAMAPTESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.