Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9350018 | 0.98 | OPRL1 (0.47) | OPRM1OPRL1OPRK1ALDH1A1TSHR | |
| SCHEMBL11161896 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRALOX15HSD17B10HDAC3 | |
| SCHEMBL6502410 | 0.77 | OPRM1 (0.41) | OPRM1OPRL1OPRK1HDAC1 | |
| SCHEMBL8284914 | 0.77 | SLC6A3 (0.56) | OPRM1OPRL1OPRK1HDAC3HDAC1 | |
| SCHEMBL3663027 | 0.77 | SLC6A3 (0.56) | OPRM1OPRL1OPRK1 | |
| SCHEMBL294762 | 0.76 | OPRM1 (0.61) | OPRM1OPRL1OPRK1 | |
| SCHEMBL8353019 | 0.76 | OPRM1 (0.43) | OPRM1OPRL1OPRK1HDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL27754809 | 0.76 | SLC6A3 (0.54) | OPRM1OPRL1OPRK1ALDH1A1TSHR | |
| SCHEMBL6501848 | 0.75 | OPRM1 (0.42) | OPRM1OPRL1OPRK1ALDH1A1HDAC1 | |
| Hydrochloric Acid SCHEMBL28148666 | 0.75 | OPRM1 (0.59) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015644-A | Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds | WARNER-LAMBERT COMPANY (US) | 1991-05-14 | — | — | US | disclosed |