Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1506043 | 0.85 | ALDH1A1 (0.66) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL9819235 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2TSHRNPC1 | |
| SCHEMBL8473671 | 0.83 | KDM4E (0.67) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL2319513 | 0.81 | KDM4E (0.64) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL15383657 | 0.80 | ALDH1A1 (0.63) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL15630697 | 0.78 | ALDH1A1 (0.70) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9819007 | 0.76 | CTDSP1 (0.43) | ALDH1A1KDM4ESMN1; SMN2TSHRMAPT | |
| SCHEMBL9818776 | 0.76 | OPRD1 (0.52) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13961307 | 0.75 | ALDH1A1 (0.64) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1461559 | 0.75 | ALDH1A1 (0.64) | ALDH1A1KDM4EMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259227-B1 | BENZHYDRYLOXYETHYL PIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Société anonyme: LES LABORATOIRES MERAM (FR) | 1991-12-27 | — | — | EP | claimed |
| US-4983614-A | ANTISPASMODIC, ANTIALLERGENIC AND ANTIHISTAMINE AGENTS | LES LABORATOIRES MERAM (FR) | 1991-01-08 | — | — | US | claimed |
| EP-0259227-A1 | Benzhydryloxyethyl piperidine derivatives, process for their preparation and pharmaceutical compositions containing them | Société anonyme: LES LABORATOIRES MERAM (FR) | 1988-03-09 | — | — | EP | claimed |
| EP-0259227-B1 | BENZHYDRYLOXYETHYL PIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Société anonyme: LES LABORATOIRES MERAM (FR) | 1991-12-27 | — | — | EP | disclosed |
| US-4983614-A | ANTISPASMODIC, ANTIALLERGENIC AND ANTIHISTAMINE AGENTS | LES LABORATOIRES MERAM (FR) | 1991-01-08 | — | — | US | disclosed |
| EP-0259227-A1 | Benzhydryloxyethyl piperidine derivatives, process for their preparation and pharmaceutical compositions containing them | Société anonyme: LES LABORATOIRES MERAM (FR) | 1988-03-09 | — | — | EP | disclosed |