Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870097 | 0.85 | SRD5A2 (0.36) | GAALMNAMAPTALDH1A1OPRD1 | |
| SCHEMBL9819011 | 0.78 | SLC6A4 (0.54) | SLC6A3SLC6A4 | |
| SCHEMBL9818773 | 0.76 | ALDH1A1 (0.61) | TSHRMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1286824 | 0.75 | RECQL (0.48) | ESR2TSHRGAALMNAMAPT | |
| SCHEMBL71975 | 0.75 | CTDSP1 (0.49) | CTDSP1TSHRGAAMDM4LMNA | |
| SCHEMBL9819235 | 0.74 | ALDH1A1 (0.42) | TSHRGAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9818776 | 0.74 | OPRD1 (0.52) | LMNAALDH1A1SMN1; SMN2OPRD1KDM4E | |
| SCHEMBL9818778 | 0.74 | CYP2D6 (0.42) | LMNAALDH1A1SLC6A2SLC6A3KDM4E | |
| SCHEMBL4579407 | 0.73 | KMT2A (0.56) | ESR2LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10258319 | 0.73 | BLM (0.51) | ESR2TSHRGAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259227-B1 | BENZHYDRYLOXYETHYL PIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Société anonyme: LES LABORATOIRES MERAM (FR) | 1991-12-27 | — | — | EP | claimed |
| US-4983614-A | ANTISPASMODIC, ANTIALLERGENIC AND ANTIHISTAMINE AGENTS | LES LABORATOIRES MERAM (FR) | 1991-01-08 | — | — | US | disclosed |