Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818808 | 0.81 | CYP2D6 (0.53) | ALDH1A1MEN1KMT2ALMNACHRM2 | |
| SCHEMBL9818773 | 0.76 | ALDH1A1 (0.61) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL9819235 | 0.74 | ALDH1A1 (0.42) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL9819007 | 0.74 | CTDSP1 (0.43) | OPRD1ALDH1A1SMN1; SMN2LMNACHRM2 | |
| Ethyl Benzoate SCHEMBL31518976 | 0.73 | LMNA (0.63) | ALDH1A1RAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL6313233 | 0.72 | MEN1 (0.58) | OPRD1ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL119521 | 0.72 | SRD5A2 (0.59) | OPRD1ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2870098 | 0.72 | LMNA (0.71) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| Cyclohexane SCHEMBL2917907 | 0.71 | CA1 (0.73) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL9678668 | 0.71 | LMNA (0.57) | OPRD1ALDH1A1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259227-B1 | BENZHYDRYLOXYETHYL PIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Société anonyme: LES LABORATOIRES MERAM (FR) | 1991-12-27 | — | — | EP | claimed |
| US-4983614-A | ANTISPASMODIC, ANTIALLERGENIC AND ANTIHISTAMINE AGENTS | LES LABORATOIRES MERAM (FR) | 1991-01-08 | — | — | US | claimed |
| EP-0259227-A1 | Benzhydryloxyethyl piperidine derivatives, process for their preparation and pharmaceutical compositions containing them | Société anonyme: LES LABORATOIRES MERAM (FR) | 1988-03-09 | — | — | EP | claimed |
| EP-0259227-B1 | BENZHYDRYLOXYETHYL PIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Société anonyme: LES LABORATOIRES MERAM (FR) | 1991-12-27 | — | — | EP | disclosed |
| US-4983614-A | ANTISPASMODIC, ANTIALLERGENIC AND ANTIHISTAMINE AGENTS | LES LABORATOIRES MERAM (FR) | 1991-01-08 | — | — | US | disclosed |
| EP-0259227-A1 | Benzhydryloxyethyl piperidine derivatives, process for their preparation and pharmaceutical compositions containing them | Société anonyme: LES LABORATOIRES MERAM (FR) | 1988-03-09 | — | — | EP | disclosed |