Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818996 | 0.87 | IDO1 (0.46) | GAAALDH1A1KDM4ELMNAIDO1 | |
| SCHEMBL9819033 | 0.86 | MEN1 (0.50) | GAAALDH1A1KDM4ELMNAIDO1 | |
| SCHEMBL9818927 | 0.80 | IDO1 (0.48) | IDO1S1PR3ARKCNQ3KCNQ2 | |
| SCHEMBL9818991 | 0.80 | IDO1 (0.49) | ALDH1A1LMNAIDO1SMN1; SMN2MEN1 | |
| SCHEMBL9818885 | 0.79 | MEN1 (0.46) | GAAALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9819046 | 0.78 | NPC1 (0.55) | GAAALDH1A1KDM4ELMNACYP3A4 | |
| SCHEMBL9819106 | 0.76 | MEN1 (0.52) | GAAALDH1A1KDM4ELMNACYP3A4 | |
| SCHEMBL10445473 | 0.74 | KMT2A (0.65) | GAAALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9818792 | 0.73 | MEN1 (0.49) | GAAKDM4ELMNAKCNQ3KCNQ2 | |
| SCHEMBL9819129 | 0.72 | KMT2A (0.54) | GAAALDH1A1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |