Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.43 |
| ▸ | CHRNG | P07510 | 1/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818991 | 0.88 | IDO1 (0.49) | MEN1KMT2AIDO1SMN1; SMN2NPC1 | |
| SCHEMBL10445473 | 0.88 | KMT2A (0.65) | MEN1KMT2AGAAATMGPR55 | |
| SCHEMBL9818885 | 0.87 | MEN1 (0.46) | MEN1KMT2AGAASMN1; SMN2NPC1 | |
| SCHEMBL9819129 | 0.86 | KMT2A (0.54) | MEN1KMT2AGAAATMGPR55 | |
| SCHEMBL9818858 | 0.86 | GAA (0.46) | MEN1KMT2AGAAATMGPR55 | |
| SCHEMBL9818792 | 0.84 | MEN1 (0.49) | MEN1KMT2AGAAATMGPR55 | |
| SCHEMBL9819133 | 0.81 | TP53 (0.50) | MEN1KMT2AGAAATMGPR55 | |
| SCHEMBL9819005 | 0.81 | TP53 (0.50) | MEN1KMT2AGAAATMGPR55 | |
| SCHEMBL9819381 | 0.80 | ALDH1A1 (0.48) | MEN1KMT2AGAAATMGPR55 | |
| SCHEMBL9818917 | 0.80 | ALDH1A1 (0.48) | MEN1KMT2AGAAATMGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |