Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819106 | 0.92 | MEN1 (0.52) | MEN1KMT2ALMNANPC1HTT | |
| SCHEMBL9819046 | 0.92 | NPC1 (0.55) | MEN1KMT2ALMNANPC1HTT | |
| SCHEMBL9819129 | 0.89 | KMT2A (0.54) | MEN1KMT2ALMNANPC1HTT | |
| SCHEMBL9819209 | 0.87 | IDO1 (0.47) | MEN1KMT2ALMNANPC1EPHX2 | |
| SCHEMBL9819033 | 0.84 | MEN1 (0.50) | MEN1KMT2ALMNANPC1HTT | |
| SCHEMBL9819133 | 0.84 | TP53 (0.50) | MEN1KMT2ALMNAHTTNLRP3 | |
| SCHEMBL9819005 | 0.84 | TP53 (0.50) | MEN1KMT2ALMNAHTTNLRP3 | |
| SCHEMBL9819077 | 0.83 | MEN1 (0.48) | MEN1KMT2ALMNANPC1HTT | |
| SCHEMBL9818917 | 0.83 | ALDH1A1 (0.48) | MEN1KMT2ALMNANPC1HTT | |
| SCHEMBL9819381 | 0.83 | ALDH1A1 (0.48) | MEN1KMT2ALMNANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | claimed |
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |