Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819133 | 0.94 | TP53 (0.50) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL9819005 | 0.94 | TP53 (0.50) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL9819381 | 0.93 | ALDH1A1 (0.48) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL9819077 | 0.93 | MEN1 (0.48) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL9818917 | 0.93 | ALDH1A1 (0.48) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL10445473 | 0.93 | KMT2A (0.65) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL9819095 | 0.92 | KMT2A (0.47) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL10445300 | 0.90 | MAPK1 (0.56) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL9819165 | 0.89 | RHOC (0.49) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL9818823 | 0.89 | RHOC (0.49) | KMT2AMEN1GAAATMGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | claimed |
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |