Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | RAPGEF3 | O95398 | 6/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819335 | 0.90 | IDO1 (0.50) | IDO1RAPGEF3RAPGEF4KCNQ3KCNQ2 | |
| SCHEMBL9818996 | 0.88 | IDO1 (0.46) | IDO1S1PR3BLM | |
| SCHEMBL9818928 | 0.85 | EPHX2 (0.50) | IDO1RAPGEF3RAPGEF4KCNQ3KCNQ2 | |
| SCHEMBL9818823 | 0.84 | RHOC (0.49) | IDO1RAPGEF3RAPGEF4KCNQ3KCNQ2 | |
| SCHEMBL9819165 | 0.84 | RHOC (0.49) | IDO1RAPGEF3RAPGEF4KCNQ3KCNQ2 | |
| SCHEMBL9819414 | 0.83 | LMNA (0.45) | IDO1RAPGEF3RAPGEF4ARKCNQ3 | |
| SCHEMBL9819209 | 0.83 | IDO1 (0.47) | IDO1RAPGEF3RAPGEF4KCNQ3KCNQ2 | |
| SCHEMBL9819035 | 0.82 | MLYCD (0.52) | — | |
| SCHEMBL9819032 | 0.82 | MLYCD (0.52) | — | |
| SCHEMBL9819042 | 0.81 | MAOB (0.47) | RAPGEF3RAPGEF4PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |