Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818900 | 1.00 | MAOB (0.41) | MAOBTBXA2RPTGDRTSHRNPC1 | |
| SCHEMBL9819044 | 0.91 | LTB4R (0.43) | MAOBSMN1; SMN2FFAR1PPARGPPARD | |
| SCHEMBL9819040 | 0.91 | LTB4R (0.43) | MAOBSMN1; SMN2FFAR1PPARGPPARD | |
| SCHEMBL9819065 | 0.87 | FFAR1 (0.41) | FFAR1PPARGPPARD | |
| SCHEMBL9819060 | 0.87 | FFAR1 (0.41) | FFAR1PPARGPPARD | |
| SCHEMBL9818925 | 0.85 | MEN1 (0.48) | NPC1RAB9ASMN1; SMN2FFAR1PPARG | |
| SCHEMBL9818920 | 0.85 | MEN1 (0.48) | NPC1RAB9ASMN1; SMN2FFAR1PPARG | |
| SCHEMBL27277358 | 0.82 | CCR2 (0.43) | MAOB | |
| SCHEMBL9819039 | 0.79 | HTT (0.40) | FFAR1PPARGPPARDHTT | |
| SCHEMBL9819041 | 0.79 | HTT (0.40) | FFAR1PPARGPPARDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230379-B1 | CHROMAN- AND THIOCHROMAN-4-ACETIC ACIDS USEFUL IN THE TREATMENT OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1991-04-03 | — | — | EP | disclosed |