Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819042 | 1.00 | MAOB (0.47) | MAOBEPHX2TRPV1PTGS1RAPGEF3 | |
| SCHEMBL9818928 | 0.96 | EPHX2 (0.50) | EPHX2TRPV1PTGS1RAPGEF3RAPGEF4 | |
| SCHEMBL9818942 | 0.90 | GSK3B (0.46) | EPHX2TRPV1PTGS1RAPGEF3RAPGEF4 | |
| SCHEMBL9818938 | 0.90 | TRPV1 (0.47) | EPHX2TRPV1PTGS1RAPGEF3RAPGEF4 | |
| SCHEMBL9818823 | 0.90 | RHOC (0.49) | EPHX2TRPV1PTGS1RAPGEF3RAPGEF4 | |
| SCHEMBL9819165 | 0.90 | RHOC (0.49) | EPHX2TRPV1PTGS1RAPGEF3RAPGEF4 | |
| SCHEMBL9819032 | 0.90 | MLYCD (0.52) | EPHX2TRPV1PTGS1RORCNPC1 | |
| SCHEMBL9819128 | 0.90 | GSK3B (0.46) | EPHX2TRPV1PTGS1RAPGEF3RAPGEF4 | |
| SCHEMBL9819082 | 0.90 | TRPV1 (0.60) | EPHX2TRPV1PTGS1RAPGEF3RAPGEF4 | |
| SCHEMBL9819366 | 0.90 | TRPV1 (0.60) | EPHX2TRPV1PTGS1RAPGEF3RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |