Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819366 | 1.00 | TRPV1 (0.60) | TRPV1EPHX2PTGS1RORCNPC1 | |
| SCHEMBL9818928 | 0.94 | EPHX2 (0.50) | TRPV1EPHX2PTGS1RORCNPC1 | |
| SCHEMBL9818907 | 0.90 | MAOB (0.47) | TRPV1EPHX2PTGS1RORCNPC1 | |
| SCHEMBL9819042 | 0.90 | MAOB (0.47) | TRPV1EPHX2PTGS1RORCNPC1 | |
| SCHEMBL9819306 | 0.89 | GSK3B (0.43) | TRPV1EPHX2NPC1RAB9AGSK3B | |
| SCHEMBL9819165 | 0.88 | RHOC (0.49) | TRPV1EPHX2PTGS1NPC1RAB9A | |
| SCHEMBL9819128 | 0.88 | GSK3B (0.46) | TRPV1EPHX2PTGS1RORCNPC1 | |
| SCHEMBL9819032 | 0.88 | MLYCD (0.52) | TRPV1EPHX2PTGS1RORCNPC1 | |
| SCHEMBL9818942 | 0.88 | GSK3B (0.46) | TRPV1EPHX2PTGS1RORCNPC1 | |
| SCHEMBL9818938 | 0.88 | TRPV1 (0.47) | TRPV1EPHX2PTGS1RORCNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |