Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.48 |
| ▸ | KLK7 | P49862 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819133 | 1.00 | TP53 (0.50) | TP53MEN1KMT2AGAAATM | |
| SCHEMBL9819129 | 0.94 | KMT2A (0.54) | TP53MEN1KMT2AGAAATM | |
| SCHEMBL9818917 | 0.88 | ALDH1A1 (0.48) | MEN1KMT2AGAAATMGPR55 | |
| SCHEMBL9819381 | 0.88 | ALDH1A1 (0.48) | MEN1KMT2AGAAATMGPR55 | |
| SCHEMBL9819077 | 0.88 | MEN1 (0.48) | TP53MEN1KMT2AGAAATM | |
| SCHEMBL10445473 | 0.87 | KMT2A (0.65) | TP53MEN1KMT2AGAAATM | |
| SCHEMBL9819165 | 0.87 | RHOC (0.49) | MEN1KMT2AGAAATMGPR55 | |
| SCHEMBL9818823 | 0.87 | RHOC (0.49) | MEN1KMT2AGAAATMGPR55 | |
| SCHEMBL9819095 | 0.86 | KMT2A (0.47) | MEN1KMT2AGAAATMGPR55 | |
| SCHEMBL9818833 | 0.86 | MEN1 (0.48) | MEN1KMT2APOLBRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |