Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819059 | 0.70 | GSTO1 (0.36) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL9819407 | 0.69 | SMN1; SMN2 (0.34) | ALDH1A1POLBMAPK14SMN1; SMN2KDM4E | |
| SCHEMBL19330984 | 0.68 | KDM4E (0.42) | ALDH1A1LMNAMAPK14ALPLKDM4E | |
| SCHEMBL6593125 | 0.67 | KDM4E (0.49) | ALDH1A1SMN1; SMN2KDM4EHPGDTSHR | |
| SCHEMBL9819221 | 0.66 | TSHR (0.39) | ALDH1A1LMNAPOLBSMN1; SMN2TSHR | |
| SCHEMBL15143655 | 0.66 | ALDH1A1 (0.39) | ALDH1A1LMNAPOLBSLC6A3SMN1; SMN2 | |
| SCHEMBL28962190 | 0.66 | SLC6A4 (0.45) | ALDH1A1LMNAPOLBSLC6A3KDM4E | |
| SCHEMBL9818989 | 0.66 | MAPT (0.41) | ALDH1A1LMNAPOLBMAPK14ALPL | |
| SCHEMBL27362505 | 0.65 | ABL1 (0.50) | ALDH1A1LMNAALPLSLC6A3SMN1; SMN2 | |
| 2-Mercaptoethanol SCHEMBL9659030 | 0.65 | CA12 (0.39) | ALDH1A1LMNAPOLBALPLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312338-B1 | SULFAMOYL-2-BENZOFURANCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4918206-A | DIURETICS, HYPOTENSIVE AGENTS; SIDE EFFECT REDUCTION | SHIONOGI & CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0312338-A1 | Sulfamoyl-2-benzofurancarboxylic acid derivatives, their preparation and use | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1989-04-19 | — | — | EP | disclosed |