Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819010 | 0.86 | GSTO1 (0.35) | GSTO1TSHRGLAALDH1A1KCNJ6 | |
| SCHEMBL9819221 | 0.79 | TSHR (0.39) | GSTO1TSHRGLACYP1A2CYP2C19 | |
| SCHEMBL9819045 | 0.73 | ALDH1A1 (0.35) | GSTO1TSHRGLACYP1A2CYP2C19 | |
| SCHEMBL9819018 | 0.70 | ALDH1A1 (0.38) | TSHRCYP1A2CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL9819407 | 0.67 | SMN1; SMN2 (0.34) | TSHRCYP1A2CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL9818966 | 0.64 | MCL1 (0.39) | GSTO1TSHRGLASMN1; SMN2ALDH1A1 | |
| SCHEMBL9436744 | 0.63 | SMN1; SMN2 (0.72) | GSTO1TSHRCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL20488862 | 0.63 | TSHR (0.57) | GSTO1TSHRGLACYP1A2CYP2C19 | |
| SCHEMBL573855 | 0.63 | VCAM1 (0.52) | TSHRCYP1A2CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL9819118 | 0.63 | ALDH1A1 (0.33) | GSTO1TSHRGLASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312338-B1 | SULFAMOYL-2-BENZOFURANCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4918206-A | DIURETICS, HYPOTENSIVE AGENTS; SIDE EFFECT REDUCTION | SHIONOGI & CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0312338-A1 | Sulfamoyl-2-benzofurancarboxylic acid derivatives, their preparation and use | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1989-04-19 | — | — | EP | disclosed |