Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818956 | 0.85 | PIM1 (0.39) | ALDH1A1RAB9ASMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9819208 | 0.79 | TSHR (0.40) | ALDH1A1RAB9ASMN1; SMN2MAPTTSHR | |
| SCHEMBL9819118 | 0.77 | ALDH1A1 (0.33) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9819059 | 0.73 | GSTO1 (0.36) | ALDH1A1SMN1; SMN2MAPTTSHRGLA | |
| SCHEMBL9819076 | 0.72 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2MAPTTSHRCYP1A2 | |
| SCHEMBL9818989 | 0.71 | MAPT (0.41) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL20604792 | 0.67 | MAOB (0.54) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL10867332 | 0.67 | CA1 (0.42) | ALDH1A1CYP1A2CYP2C19LMNA | |
| SCHEMBL11530620 | 0.66 | MAPT (0.44) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9819399 | 0.66 | MAPT (0.37) | ALDH1A1SMN1; SMN2MAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1100164-A | — | — | None | — | — | JP | disclosed |
| EP-0312338-B1 | SULFAMOYL-2-BENZOFURANCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4918206-A | DIURETICS, HYPOTENSIVE AGENTS; SIDE EFFECT REDUCTION | SHIONOGI & CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0312338-A1 | Sulfamoyl-2-benzofurancarboxylic acid derivatives, their preparation and use | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1989-04-19 | — | — | EP | disclosed |
| JP-H01100164-A | SULFAMOYL-2-BENZOFURANCARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO LTD | 1989-04-18 | — | — | JP | disclosed |