Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819352 | 0.91 | TSHR (0.43) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9819414 | 0.87 | LMNA (0.45) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9819097 | 0.83 | P2RX1 (0.50) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9819202 | 0.80 | KMT2A (0.46) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9819381 | 0.79 | ALDH1A1 (0.48) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9818917 | 0.79 | ALDH1A1 (0.48) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9819190 | 0.78 | AR (0.58) | LMNASMN1; SMN2ALDH1A1HTTCYP1A2 | |
| SCHEMBL9819106 | 0.76 | MEN1 (0.52) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9819100 | 0.75 | MEN1 (0.48) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9818833 | 0.75 | MEN1 (0.48) | MAPTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |