Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819101 | 0.91 | MAPT (0.41) | TSHRMAPK1MEN1KMT2ALMNA | |
| SCHEMBL9819097 | 0.91 | P2RX1 (0.50) | MAPK1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9819414 | 0.89 | LMNA (0.45) | TSHRMAPK1MEN1KMT2ALMNA | |
| SCHEMBL9819190 | 0.86 | AR (0.58) | TSHRMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9819106 | 0.85 | MEN1 (0.52) | MAPK1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9818807 | 0.82 | APP (0.52) | MAPK1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9819129 | 0.82 | KMT2A (0.54) | TSHRMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9818996 | 0.81 | IDO1 (0.46) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL9818792 | 0.77 | MEN1 (0.49) | TSHRMEN1KMT2ALMNAGAA | |
| SCHEMBL9819046 | 0.77 | NPC1 (0.55) | MAPK1MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |