SCHEMBL9819161

SCHEMBL9819161

CCCCNC(=O)NS(=O)(=O)c1cccc2c1nnn2C

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 7/20 0.49
CYP2C9 P11712 3/20 0.47
ALDH1A1 P00352 2/20 0.47
LMNA P02545 1/20 0.47
ALB P02768 1/20 0.47
TSHR P16473 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CCKBR P32239 1/20 0.43
CYP2C19 P33261 1/20 0.42
HTT P42858 1/20 0.42
PPARG P37231 1/20 0.41
TBXA2R P21731 4/20 0.41
PTGER1 P34995 1/20 0.41
PTGER3 P43115 1/20 0.41
AGTR1 P30556 1/20 0.40
AGTR2 P50052 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9819350 0.81 CCKBR (0.42) ALDH1A1LMNATSHRCCKBRHTT
SCHEMBL16758296 0.73 CYP2C9 (0.62) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL10565360 0.72 FBP1 (0.47) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL10473854 0.71 CYP2C9 (0.56) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL10642741 0.71 CYP2C9 (0.56) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL10681455 0.71 ALDH1A1 (0.53) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL9824047 0.70 PTGER1 (0.48) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL8448505 0.70 CYP2C9 (0.54) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL10569228 0.70 CYP2C9 (0.54) FBP1CYP2C9ALDH1A1LMNAALB
SCHEMBL6464360 0.70 PTGER1 (0.59) FBP1CYP2C9ALDH1A1LMNAALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0404758-A1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-02 EP disclosed
EP-0404758-A4 HERBICIDAL SULFONAMIDES. DU PONT (US) 1989-08-30 EP disclosed
US-4854962-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-08-08 US disclosed
US-4746356-A Herbicidal sulfonamides E. I. DUPONT DE NEMOURS AND COMPANY (US) 1988-05-24 US disclosed
WO-1987007114-A1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-12-03 WO disclosed