Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | TEX264 | Q9Y6I9 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819176 | 0.85 | APP (0.46) | TP53APPTEX264ABL1RIN1 | |
| SCHEMBL9819413 | 0.84 | TSHR (0.37) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9819200 | 0.74 | KMT2A (0.34) | APPKMT2A | |
| SCHEMBL9819181 | 0.74 | APP (0.48) | TP53APPTEX264ABL1RIN1 | |
| SCHEMBL9818958 | 0.68 | MCL1 (0.40) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11712969 | 0.67 | KMT2A (0.71) | TP53APPTEX264ABL1RIN1 | |
| SCHEMBL9819208 | 0.66 | TSHR (0.40) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9819158 | 0.66 | SMN1; SMN2 (0.49) | TP53MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL14367385 | 0.64 | APP (0.51) | TP53APPTEX264ABL1RIN1 | |
| Hydrochloric Acid SCHEMBL9040981 | 0.63 | CNR2 (0.47) | TP53APPTEX264ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312338-B1 | SULFAMOYL-2-BENZOFURANCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-12-27 | — | — | EP | claimed |