Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | IL18 | Q14116 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819202 | 0.93 | KMT2A (0.46) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL9819214 | 0.93 | GSK3B (0.51) | GSK3BIDO1MLYCDMAPTLMNA | |
| SCHEMBL9819100 | 0.88 | MEN1 (0.48) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL9818833 | 0.88 | MEN1 (0.48) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL9819392 | 0.86 | CNR1 (0.47) | GSK3BMAPTLMNAMEN1KMT2A | |
| SCHEMBL9819381 | 0.86 | ALDH1A1 (0.48) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL9818917 | 0.86 | ALDH1A1 (0.48) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL9819032 | 0.83 | MLYCD (0.52) | GSK3BMLYCDRAB9ANPC1HDAC1 | |
| SCHEMBL9819035 | 0.83 | MLYCD (0.52) | GSK3BMLYCDRAB9ANPC1HDAC1 | |
| SCHEMBL9819128 | 0.83 | GSK3B (0.46) | GSK3BMAPTRAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |