Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAPGEF3 | O95398 | 3/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819335 | 0.93 | IDO1 (0.50) | IDO1MEN1KMT2ALMNARAPGEF3 | |
| SCHEMBL9818928 | 0.88 | EPHX2 (0.50) | IDO1RAPGEF3RAPGEF4KCNQ3KCNQ2 | |
| SCHEMBL9818823 | 0.87 | RHOC (0.49) | IDO1MEN1KMT2ALMNARAPGEF3 | |
| SCHEMBL9819165 | 0.87 | RHOC (0.49) | IDO1MEN1KMT2ALMNARAPGEF3 | |
| SCHEMBL9818792 | 0.87 | MEN1 (0.49) | MEN1KMT2ALMNAKCNQ3KCNQ2 | |
| SCHEMBL9819046 | 0.86 | NPC1 (0.55) | MEN1KMT2ALMNAKCNQ3KCNQ2 | |
| SCHEMBL9819122 | 0.86 | IDO1 (0.47) | IDO1LMNARAPGEF3RAPGEF4KCNQ3 | |
| SCHEMBL9818991 | 0.85 | IDO1 (0.49) | IDO1MEN1KMT2ALMNAMAPT | |
| SCHEMBL9818907 | 0.84 | MAOB (0.47) | MEN1KMT2ALMNARAPGEF3RAPGEF4 | |
| SCHEMBL9819042 | 0.84 | MAOB (0.47) | MEN1KMT2ALMNARAPGEF3RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |