Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 6/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819254 | 0.83 | RXRA (0.44) | FFAR1HDAC6F2 | |
| SCHEMBL11876392 | 0.81 | HDAC6 (0.38) | MLYCDROCK2MTORHDAC6PTPN1 | |
| SCHEMBL9819339 | 0.80 | ROCK2 (0.43) | FFAR1ROCK2 | |
| SCHEMBL23804581 | 0.74 | MLYCD (0.49) | MLYCDROCK2MTOREPHX2 | |
| SCHEMBL11821275 | 0.74 | EPHX2 (0.43) | MTORHDAC6EPHX2 | |
| SCHEMBL20472411 | 0.73 | ROCK2 (0.46) | MLYCDROCK2 | |
| SCHEMBL7837974 | 0.72 | MLYCD (0.50) | MLYCDPTPN1 | |
| SCHEMBL20472413 | 0.71 | MLYCD (0.43) | MLYCDROCK2 | |
| SCHEMBL6229257 | 0.71 | MLYCD (0.54) | MLYCDMTORSERPINE1 | |
| SCHEMBL27949212 | 0.71 | FFAR1 (0.42) | MLYCDFFAR1MTORPTPN1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162669-B1 | ANTICONVULSIVE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4588729-A | Treating convulsions with dihydrouracil derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |