Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3552942 | 0.84 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1KDM4EGBA1GAA | |
| Hydrochloric Acid SCHEMBL28406920 | 0.80 | CYP1B1 (0.44) | L3MBTL1ALDH1A1KDM4EGBA1TSHR | |
| SCHEMBL7283175 | 0.78 | MAPT (0.51) | L3MBTL1FAAHMGLLALDH1A1KDM4E | |
| SCHEMBL15147751 | 0.76 | PDE5A (0.65) | L3MBTL1ALDH1A1KDM4EGBA1LMNA | |
| SCHEMBL28002627 | 0.75 | TLR8 (0.54) | L3MBTL1FAAHMGLLALDH1A1KDM4E | |
| SCHEMBL1995850 | 0.75 | NR1I3 (0.56) | ALDH1A1KDM4EMAPTHPGDCYP1A2 | |
| SCHEMBL27294581 | 0.75 | RAB9A (0.64) | L3MBTL1FAAHMGLLALDH1A1KDM4E | |
| SCHEMBL27374633 | 0.75 | RAB9A (0.64) | L3MBTL1FAAHMGLLALDH1A1KDM4E | |
| SCHEMBL6722631 | 0.75 | TLR8 (0.47) | ALDH1A1KDM4EGAATLR8LMNA | |
| SCHEMBL28407242 | 0.74 | LMNA (0.43) | L3MBTL1ALDH1A1KDM4EGBA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302967-B1 | QUINAZOLINE DERIVATIVE, PROCESSES FOR ITS PRODUCTION, AND CEREBRAL DYSFUNCTION REMEDYING AGENT COMPRISING IT AS ACTIVE INGREDIENT | KANEBO, LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4877790-A | NERVOUS SYSTEM DISORDERS; ALZHEIMER'S DISEASE | KANEBO LIMITED (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0302967-A2 | Quinazoline derivative, processes for its production, and cerebral dysfunction remedying agent comprising it as active ingredient | KANEBO, LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |