Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CASP6 | P55212 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534856 | 0.84 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1MAPTKDM4EALDH1A1 | |
| SCHEMBL9819760 | 0.73 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1MAPTKDM4EALDH1A1 | |
| SCHEMBL34471106 | 0.71 | MEN1 (0.53) | HSP90AA1HSP90AB1MAPTKDM4EALDH1A1 | |
| SCHEMBL20746698 | 0.69 | MMP2 (0.33) | CHRM1METAP2 | |
| Dnqx SCHEMBL1258964 | 0.68 | POLB (0.57) | HSP90AA1HSP90AB1MAPTKDM4EALDH1A1 | |
| SCHEMBL9670886 | 0.68 | MAPT (0.65) | HSP90AA1HSP90AB1MAPTKDM4EALDH1A1 | |
| SCHEMBL1351219 | 0.67 | POLB (0.50) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL21638318 | 0.67 | MEN1 (0.51) | HSP90AA1HSP90AB1MAPTKDM4EALDH1A1 | |
| SCHEMBL9535035 | 0.67 | CTSB (0.41) | HSP90AA1HSP90AB1MAPTALDH1A1MEN1 | |
| SCHEMBL18743108 | 0.66 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057516-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-10-15 | — | — | US | disclosed |