Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.66 |
| ▸ | KCNJ1 | P48048 | 4/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.61 |
| ▸ | HRH1 | P35367 | 4/20 | 0.61 |
| ▸ | HRH2 | P25021 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NMT1 | P30419 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498982 | 0.85 | KCNJ1 (0.67) | SIGMAR1KCNJ1KCNH2HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL7986766 | 0.84 | KCNJ1 (0.65) | SIGMAR1KCNJ1KCNH2HRH3HRH1 | |
| SCHEMBL5751863 | 0.80 | SIGMAR1 (0.70) | SIGMAR1KCNJ1KCNH2NMT1 | |
| SCHEMBL11630606 | 0.80 | SIGMAR1 (0.70) | SIGMAR1KCNJ1KCNH2HRH3HRH1 | |
| SCHEMBL15651128 | 0.80 | SIGMAR1 (0.70) | SIGMAR1KCNJ1KCNH2HTR1ADRD4 | |
| SCHEMBL9319743 | 0.80 | SIGMAR1 (0.70) | SIGMAR1KCNJ1KCNH2HRH3HRH1 | |
| SCHEMBL13858201 | 0.80 | SIGMAR1 (0.70) | SIGMAR1KCNJ1KCNH2NMT1 | |
| SCHEMBL5754907 | 0.80 | SIGMAR1 (0.70) | SIGMAR1KCNJ1KCNH2HTR1AHTR2A | |
| SCHEMBL457139 | 0.80 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL10677264 | 0.80 | SIGMAR1 (1.00) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240190821-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL)BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES INC (US) | 2024-06-13 | — | — | US | disclosed |
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240190821-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL)BENZENESULFONAMIDES AND USES THEREOF | PACSIN2, TPX2, PRSS12 | SIGMAR1 2935/4885KCNJ1 4707/4885KCNH2 4786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.