Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | BLM | P54132 | 2/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.68 |
| ▸ | MPO | P05164 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tryptophan SCHEMBL1716928 | 0.89 | KDM4E (0.74) | MAPTKDM4ELMNAKMT2AMEN1 | |
| SCHEMBL8542052 | 0.85 | NOS3 (0.49) | MAPTKDM4ELMNAKMT2AMEN1 | |
| SCHEMBL8542049 | 0.85 | NOS3 (0.49) | MAPTKDM4ELMNAKMT2AMEN1 | |
| Dl-Tryptophan SCHEMBL5065247 | 0.83 | KDM4E (0.89) | MAPTKDM4ELMNAKMT2AMEN1 | |
| Tryptophan SCHEMBL5065251 | 0.83 | KDM4E (0.89) | MAPTKDM4ELMNAKMT2AMEN1 | |
| Dl-Tryptophan SCHEMBL27748750 | 0.83 | KDM4E (0.94) | MAPTKDM4ELMNAKMT2AMEN1 | |
| Tryptophan SCHEMBL27748748 | 0.83 | KDM4E (0.94) | MAPTKDM4ELMNAKMT2AMEN1 | |
| Dl-Tryptophan SCHEMBL28580277 | 0.83 | KDM4E (0.94) | MAPTKDM4ELMNAKMT2AMEN1 | |
| Tryptophan SCHEMBL23141133 | 0.82 | KMT2A (1.00) | MAPTKDM4ELMNAKMT2AMEN1 | |
| Tryptophan SCHEMBL475350 | 0.82 | KMT2A (1.00) | MAPTKDM4ELMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061693-A | Hexapeptides, anticoagulants | MERCK & CO., INC. (US) | 1991-10-29 | — | — | US | disclosed |
| EP-0410767-A1 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1991-01-30 | — | — | EP | disclosed |