Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPSE | Q9Y251 | 8/20 | 0.56 |
| ▸ | UTRN | P46939 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820079 | 0.83 | HPSE (0.72) | MAPTTP53SMN1; SMN2HPSEKDM4E | |
| Methane SCHEMBL506232 | 0.82 | HPSE (0.70) | MAPTTP53SMN1; SMN2HPSEKDM4E | |
| SCHEMBL1904985 | 0.79 | NPC1 (0.57) | MAPTSMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL3741336 | 0.79 | MAOB (0.55) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9820106 | 0.79 | MAPT (0.55) | MAPTTP53SMN1; SMN2UTRNNPC1 | |
| SCHEMBL5641397 | 0.78 | MAPT (0.55) | MAPTTP53SMN1; SMN2HPSEUTRN | |
| SCHEMBL6818285 | 0.77 | NPC1 (0.67) | MAPTTP53SMN1; SMN2HPSENPC1 | |
| SCHEMBL6821837 | 0.77 | NPC1 (0.67) | MAPTSMN1; SMN2HPSENPC1KDM4E | |
| SCHEMBL14581704 | 0.76 | KDM4E (0.66) | MAPTTP53SMN1; SMN2HPSENPC1 | |
| SCHEMBL5641355 | 0.75 | MAPT (0.55) | MAPTTP53SMN1; SMN2HPSEUTRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182061-B1 | NEW PROCESS FOR PREPARING 2(4-FLUOROPHENYL) ALPHA METHYL-5-BENZOXAZOLE ACETIC ACID | RAVIZZA S.p.A. (IT) | 1991-12-27 | — | — | EP | disclosed |
| US-4652654-A | Process for preparing 2(4-fluorophenyl)alpha-methyl-5-benzoxazole acetic acid | RAVIZZA SPA (IT) | 1987-03-24 | — | — | US | disclosed |
| EP-0182061-A1 | New process for preparing 2(4-fluorophenyl) alpha methyl-5-benzoxazole acetic acid | RAVIZZA S.p.A. (IT) | 1986-05-28 | — | — | EP | disclosed |