Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 6/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528176 | 0.87 | HSP90AA1 (0.55) | ALDH1A1HTTHSP90AA1NPSR1TDP1 | |
| SCHEMBL29189790 | 0.77 | CA12 (0.61) | ALDH1A1HPGDKMT2AMEN1MAPK1 | |
| SCHEMBL15991866 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HTTHSP90AA1NPSR1TDP1 | |
| SCHEMBL15991987 | 0.76 | ALDH1A1 (0.56) | ALDH1A1HTTHSP90AA1NPSR1TDP1 | |
| SCHEMBL15991953 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HTTHSP90AA1NPSR1TDP1 | |
| SCHEMBL300884 | 0.74 | CA12 (0.42) | ALDH1A1TDP1HPGDMGLLKMT2A | |
| SCHEMBL15991754 | 0.74 | ALDH1A1 (0.47) | ALDH1A1HTTHSP90AA1NPSR1TDP1 | |
| SCHEMBL10328161 | 0.74 | NSD2 (0.53) | ALDH1A1HTTHSP90AA1NPSR1TDP1 | |
| SCHEMBL10328160 | 0.74 | NSD2 (0.49) | ALDH1A1HTTHSP90AA1NPSR1TDP1 | |
| SCHEMBL17071632 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TDP1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073540-A | Polypeptide sequence for regulating surface membrane receptor response, insulin, epidermal growth factor | RECEPTRON (US) | 1991-12-17 | — | — | US | disclosed |