Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820794 | 0.84 | ALDH1A1 (0.33) | GAANPC1PKMHTTALDH1A1 | |
| SCHEMBL9869965 | 0.74 | CYP1A2 (0.35) | GAAALDH1A1KMT2ATDP1POLB | |
| SCHEMBL9820813 | 0.74 | MAOA (0.42) | NPC1HTTALDH1A1KMT2ATDP1 | |
| SCHEMBL9820696 | 0.72 | MAOA (0.31) | KMT2A | |
| SCHEMBL9820690 | 0.72 | MAOA (0.31) | KMT2A | |
| SCHEMBL9820587 | 0.69 | ALDH1A1 (0.31) | ALDH1A1HPGD | |
| SCHEMBL9820645 | 0.69 | MAOA (0.31) | — | |
| SCHEMBL9820650 | 0.69 | MAOA (0.31) | — | |
| SCHEMBL9820850 | 0.63 | MAOA (0.39) | ALDH1A1HPGDBCL2L1KMT2ATDP1 | |
| SCHEMBL10664901 | 0.62 | ALDH1A1 (0.38) | NPC1ALDH1A1HPGDKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |