Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821148 | 0.71 | LMNA (0.38) | RAB9ANPC1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL9820961 | 0.71 | TSHR (0.34) | KMT2AMEN1POLB | |
| SCHEMBL10367499 | 0.71 | SIGMAR1 (0.45) | SIGMAR1KMT2AMEN1PRKDCRAB9A | |
| SCHEMBL12449601 | 0.68 | SIGMAR1 (0.58) | SIGMAR1KMT2AMEN1PRKDCRAB9A | |
| SCHEMBL270530 | 0.68 | SIGMAR1 (0.67) | SIGMAR1KMT2AALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL15503144 | 0.67 | SIGMAR1 (0.65) | SIGMAR1KMT2AALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL15503302 | 0.67 | SIGMAR1 (0.65) | SIGMAR1KMT2AALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL23805529 | 0.66 | SIGMAR1 (0.82) | SIGMAR1KMT2AMEN1POLBHRH3 | |
| SCHEMBL12449602 | 0.66 | SIGMAR1 (0.51) | SIGMAR1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL270272 | 0.64 | MAPT (0.65) | SIGMAR1KMT2AMEN1PRKDCRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188887-B1 | TERTIARY AMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-02 | — | — | EP | disclosed |
| EP-0188887-A1 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-30 | — | — | EP | disclosed |