SCHEMBL9820918

SCHEMBL9820918

C=CCOc1cccc2ccc(=O)[nH]c12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.47
CA9 Q16790 5/20 0.47
CYP3A4 P08684 1/20 0.44
CYP2A6 P11509 1/20 0.44
CA1 P00915 2/20 0.41
LIG1 P18858 1/20 0.40
HPGD P15428 2/20 0.40
TXNRD1 Q16881 1/20 0.39
TXNRD3 Q86VQ6 1/20 0.39
TXNRD2 Q9NNW7 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CCR1 P32246 2/20 0.38
KCNH2 Q12809 2/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10064553 0.77 MCHR1 (0.48) CA12CA9GAA
SCHEMBL12313404 0.77 MAPT (0.47) CA12CA9MAPTMAPK1NPC1
SCHEMBL9820774 0.76 MCHR1 (0.49) CA12CA9CYP3A4GAAMAPT
Charcoal, Activated SCHEMBL30421850 0.76 MAPT (0.46) CA12CA9MAPTMAPK1NPC1
SCHEMBL1114643 0.75 CA12 (0.55) CA12CA9CYP2A6CA1HPGD
SCHEMBL11863877 0.74 ALDH1A1 (0.48) CA12CA9CYP3A4CA1HPGD
SCHEMBL1137674 0.74 RAB9A (0.46) CA12CA9RAB9A
SCHEMBL1137647 0.74 CA12 (0.43) CA12CA9KDM4EMAPTNPC1
SCHEMBL11242304 0.73 DRD2 (0.52) CA12CA9CYP3A4CYP2A6CA1
SCHEMBL11278744 0.73 CA12 (0.42) CA12CA9CYP3A4MAPTCCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0264951-B1 PROCESS FOR STABILISING PROCATEROL WARNER-LAMBERT COMPANY (US) 1991-09-11 EP disclosed
EP-0264951-A2 Process for stabilising procaterol WARNER-LAMBERT COMPANY (US) 1988-04-27 EP disclosed
US-4687776-A FORMING DERIVATIVES OF PROCATEROL WARNER-LAMBERT COMPANY (US) 1987-08-18 US disclosed