Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682242 | 0.85 | MEN1 (0.48) | LMNANPC1RAB9ACYP2D6CYP2C9 | |
| SCHEMBL10490539 | 0.80 | ESR2 (0.52) | ESR2ESR1GRM2GRM3GRM4 | |
| SCHEMBL9821044 | 0.80 | ESR1 (0.47) | ESR2ESR1TSHRRORCNPC1 | |
| Hydroquinone SCHEMBL9422498 | 0.80 | NPC1 (0.48) | ESR2ESR1ALOX15TDP1LMNA | |
| SCHEMBL45825 | 0.78 | ESR2 (0.64) | ESR2ESR1ALOX15LMNAMTOR | |
| SCHEMBL8908857 | 0.76 | ESR2 (0.61) | ESR2ESR1 | |
| SCHEMBL8907518 | 0.76 | ESR1 (0.43) | ESR2ESR1LMNATSHRCA12 | |
| SCHEMBL3811364 | 0.75 | ESR2 (0.80) | ESR2ESR1ALOX15LMNAMTOR | |
| SCHEMBL7530533 | 0.75 | ESR2 (0.80) | ESR2ESR1ALOX15LMNAMTOR | |
| SCHEMBL237553 | 0.75 | ESR2 (0.59) | ESR2ESR1CYP2C19CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240362-B1 | PROCESS FOR THE PREPARATION OF 4'-HYDROXYBIPHENYL-4-CARBOXYLIC ACID | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-12-11 | — | — | EP | claimed |
| EP-0238305-B1 | 4,4-BIS(4-HYDROXYPHENYL)CYCLOHEXANECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | claimed |
| US-4814488-A | STARTING MATERIALS FOR POLYMERS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1989-03-21 | — | — | US | claimed |
| US-4755616-A | 4,4-bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1988-07-05 | — | — | US | claimed |
| US-4755617-A | Process for the preparation of 4'-hydroxybiphenyl-4-carboxyl acid | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1988-07-05 | — | — | US | claimed |
| EP-0240362-A2 | Process for the preparation of 4'-hydroxybiphenyl-4-carboxylic acid | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-10-07 | — | — | EP | claimed |
| EP-0238305-A1 | 4,4-Bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-09-23 | — | — | EP | claimed |
| JP-1289827-A | — | — | None | — | — | JP | disclosed |
| JP-62238235-A | — | — | None | — | — | JP | disclosed |
| JP-63014756-A | — | — | None | — | — | JP | disclosed |
| EP-0240362-B1 | PROCESS FOR THE PREPARATION OF 4'-HYDROXYBIPHENYL-4-CARBOXYLIC ACID | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |
| EP-0238305-B1 | 4,4-BIS(4-HYDROXYPHENYL)CYCLOHEXANECARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PREPARING SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |
| JP-H01289827-A | NEW AROMATIC POLYESTER AND ITS PRODUCTION | MITSUI TOATSU CHEM INC | 1989-11-21 | — | — | JP | disclosed |
| JP-S6314756-A | PRODUCTION OF 4'-HYDROXYBIPHENYL-4-CARBOXYLIC ACID | MITSUI TOATSU CHEM INC | 1988-01-21 | — | — | JP | disclosed |
| JP-S62238235-A | PRODUCTION OF 4'-HYDROXYBIPHENYL-4-CARBOXYLIC ACID | MITSUI TOATSU CHEM INC | 1987-10-19 | — | — | JP | disclosed |
| EP-0240362-A2 | Process for the preparation of 4'-hydroxybiphenyl-4-carboxylic acid | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-10-07 | — | — | EP | disclosed |
| EP-0240362-A2 | Process for the preparation of 4'-hydroxybiphenyl-4-carboxylic acid | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-10-07 | — | — | EP | disclosed |
| EP-0238305-A1 | 4,4-Bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-09-23 | — | — | EP | disclosed |
| EP-0238305-A1 | 4,4-Bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-09-23 | — | — | EP | disclosed |
| EP-0238305-A1 | 4,4-Bis(4-hydroxyphenyl)cyclohexanecarboxylic acid derivatives and process for preparing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-09-23 | — | — | EP | disclosed |