Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 3/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822031 | 0.88 | KDM4E (0.41) | ALDH1A1POLBKDM4EMAPTLMNA | |
| SCHEMBL9822008 | 0.86 | ALDH1A1 (0.39) | ALDH1A1POLBKDM4EMAPTNNMT | |
| SCHEMBL9822341 | 0.83 | ALDH1A1 (0.37) | ALDH1A1POLBKDM4EMAPTLMNA | |
| SCHEMBL9822024 | 0.76 | KDM4E (0.40) | ALDH1A1POLBKDM4EMAPTLMNA | |
| SCHEMBL9822487 | 0.74 | KDM4E (0.35) | ALDH1A1POLBKDM4EMAPTLMNA | |
| SCHEMBL9822162 | 0.69 | PKM (0.35) | ALDH1A1POLBKDM4EMAPTLMNA | |
| SCHEMBL9822338 | 0.69 | ALDH1A1 (0.36) | ALDH1A1POLBKDM4EMAPTKMT2A | |
| SCHEMBL9822481 | 0.68 | KDM4E (0.35) | ALDH1A1POLBKDM4EMAPTLMNA | |
| SCHEMBL9822234 | 0.67 | HCAR2 (0.39) | ALDH1A1KDM4ELMNA | |
| SCHEMBL9822083 | 0.65 | PKM (0.39) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |