Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822316 | 0.87 | KDM4E (0.41) | ALDH1A1POLBKDM4EMAPTKMT2A | |
| SCHEMBL9822341 | 0.84 | ALDH1A1 (0.37) | ALDH1A1POLBKDM4EMAPTKMT2A | |
| SCHEMBL9822273 | 0.74 | KDM4E (0.42) | ALDH1A1POLBKDM4EMAPTKMT2A | |
| SCHEMBL9822062 | 0.70 | LMNA (0.35) | ALDH1A1POLBKDM4EMAPTCLK4 | |
| SCHEMBL9822014 | 0.69 | ALDH1A1 (0.40) | ALDH1A1POLBKDM4EMAPTKMT2A | |
| SCHEMBL9821978 | 0.67 | SORD (0.42) | ALDH1A1POLBKDM4ENPC1RAB9A | |
| SCHEMBL10408156 | 0.67 | POLB (0.58) | ALDH1A1POLBKDM4EMAPTKMT2A | |
| SCHEMBL9822069 | 0.64 | LMNA (0.35) | ALDH1A1POLBKDM4EMAPTCLK4 | |
| SCHEMBL9822217 | 0.63 | KDM4E (0.40) | ALDH1A1POLBKDM4EMAPTKMT2A | |
| SCHEMBL10407734 | 0.63 | ALDH1A1 (0.59) | ALDH1A1POLBKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |