SCHEMBL9822583

SCHEMBL9822583

CCN(c1ccccc1C)S(=O)(=O)O

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.48
ALDH1A1 P00352 1/20 0.46
MAPT P10636 3/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 2/20 0.45
LMNA P02545 1/20 0.45
TEAD1 P28347 1/20 0.43
PER2 O15055 1/20 0.43
CRY1 Q16526 1/20 0.43
CRY2 Q49AN0 1/20 0.43
POLB P06746 2/20 0.42
TSHR P16473 1/20 0.40
NSD2 O96028 1/20 0.39
APEX1 P27695 1/20 0.39
RECQL P46063 1/20 0.39
ESR2 Q92731 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9436336 0.84 ALDH1A1 (0.42) ESR1ALDH1A1MAPTTP53CYP3A4
SCHEMBL19337154 0.83 ALDH1A1 (0.59) ESR1ALDH1A1MAPTTP53CYP3A4
SCHEMBL9822673 0.81 LMNA (0.42) ESR1ALDH1A1LMNATSHR
SCHEMBL6275266 0.81 TEAD1 (0.57) ESR1ALDH1A1TEAD1TSHR
SCHEMBL10655854 0.80 IDH1 (0.40) ESR1MAPTTEAD1POLBTSHR
SCHEMBL7045573 0.79 PER2 (0.34) ESR1ALDH1A1MAPTTP53CYP3A4
SCHEMBL10658420 0.79 TEAD1 (0.38) ESR1ALDH1A1MAPTCYP3A4LMNA
SCHEMBL10655590 0.78 PTPN1 (0.45) ESR1TEAD1L3MBTL1
SCHEMBL7045577 0.78 CYP4F2 (0.33) ESR1ALDH1A1MAPTTP53CYP3A4
SCHEMBL6309662 0.77 ESR1 (0.39) ESR1ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0291588-B1 SIZING AGENT KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1991-09-04 EP disclosed
EP-0224976-B1 METHOD OF SIZING PAPER KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1989-10-18 EP disclosed
US-4826570-A PARTIAL ESTER OF ALKENYL SUCCINIC ACID, PAPERMAKING KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1989-05-02 US disclosed
EP-0291588-A1 Sizing agent KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1988-11-23 EP disclosed
EP-0224976-A1 Method of sizing paper KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1987-06-10 EP disclosed