Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 6/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10658420 | 0.83 | TEAD1 (0.38) | MAPTESR1CYP3A4LMNATSHR | |
| SCHEMBL10655854 | 0.79 | IDH1 (0.40) | MAPTESR1TSHRPOLBNSD2 | |
| SCHEMBL9822583 | 0.78 | ESR1 (0.48) | TP53MAPTESR1CYP3A4LMNA | |
| SCHEMBL9436336 | 0.77 | ALDH1A1 (0.42) | TP53MAPTESR1CYP3A4LMNA | |
| SCHEMBL1592206 | 0.75 | ALDH1A1 (0.37) | TP53MAPTESR1TSHRKDM4E | |
| SCHEMBL7045573 | 0.72 | PER2 (0.34) | TP53MAPTESR1CYP3A4LMNA | |
| SCHEMBL9865191 | 0.72 | KDM4E (0.46) | CYP4F2CYP4A11TSHRPOLBKDM4E | |
| SCHEMBL28475588 | 0.71 | HTR6 (0.33) | MAPTESR1CYP3A4LMNATSHR | |
| Ammonia Solution, Strong SCHEMBL28843868 | 0.70 | KDM4E (0.44) | CYP4F2CYP4A11TSHRPOLBKDM4E | |
| SCHEMBL10988499 | 0.69 | ESR1 (0.40) | TP53MAPTESR1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5755231-A | Test strip including integral specimen flow retarding structure | PLUS BIO, INC. (US) | 1998-05-26 | — | — | US | claimed |
| WO-1998000703-A1 | TEST STRIP INCLUDING INTEGRAL SPECIMEN FLOW RETARDING STRUCTURE | PLUS BIO, INC. (US) | 1998-01-08 | — | — | WO | claimed |
| EP-0806671-B1 | Automated urinalysis system for detecting blood in urine | CHIMERA RES AND CHEMICAL INC (US) | 2003-04-16 | — | — | EP | disclosed |
| EP-0539495-B1 | DEVICE AND METHOD FOR MEASURING HDL-CHOLESTEROL EMPLOYING PRECIPITATION ON A SOLID-PHASE | CHOLESTECH CORP (US) | 2001-01-17 | — | — | EP | disclosed |
| EP-1028319-A2 | Device and method for measuring HDL-cholesterol emplying precipitation on a solid-phase | CHOLESTECH CORPORATION (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5755231-A | Test strip including integral specimen flow retarding structure | PLUS BIO, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| US-5733785-A | QUANTITATIVE ANALYSIS | CHINERA RESEARCH CHEMICAL, INC. (US) | 1998-03-31 | — | — | US | disclosed |
| WO-1998000703-A1 | TEST STRIP INCLUDING INTEGRAL SPECIMEN FLOW RETARDING STRUCTURE | PLUS BIO, INC. (US) | 1998-01-08 | — | — | WO | disclosed |
| EP-0806671-A1 | Automated urinalysis system for detecting blood in urine | Chimera Research and Chemical, Inc. (US) | 1997-11-12 | — | — | EP | disclosed |
| US-5516700-A | Automated urinalysis method | CHIMERA RESEARCH AND CHEMICAL, INC. (US) | 1996-05-14 | — | — | US | disclosed |
| US-5451370-A | Analysis for cholesterol and lipoproteins with fiber pads for blood, glass fibers and reservoirs | CHOLESTECH CORPORATION (US) | 1995-09-19 | — | — | US | disclosed |
| US-5213965-A | Measuring high density lipoprotein concentration | CHOLESTECH CORPORATION (US) | 1993-05-25 | — | — | US | disclosed |
| US-5213964-A | Separation from low density lipoproteins using glass fiber filter treated with polyvinyl alcohol or an aminosilane | CHOLESTECH CORPORATION (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0539495-A1 | SOLID-PHASE PRECIPITATION ASSAY DEVICE AND METHOD | CHOLESTECH CORPORATION (US) | 1993-05-05 | — | — | EP | disclosed |
| WO-1992001498-A2 | SOLID-PHASE PRECIPITATION ASSAY DEVICE AND METHOD | CHOLESTECH CORPORATION (US) | 1992-02-06 | — | — | WO | disclosed |