Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67558 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HSD17B10TDP1CYP3A4MAPK1 | |
| SCHEMBL5564527 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1CYP3A4MAPK1 | |
| SCHEMBL9822755 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1CYP3A4MAPK1 | |
| SCHEMBL9822519 | 0.77 | CA2 (0.47) | ALDH1A1HSD17B10TDP1CYP3A4MAPK1 | |
| SCHEMBL995084 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TDP1CYP3A4MAPK1 | |
| SCHEMBL8589523 | 0.71 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1CYP3A4MAPK1 | |
| SCHEMBL651902 | 0.71 | ALDH1A1 (0.71) | ALDH1A1HSD17B10TDP1CYP3A4MAPK1 | |
| Chlorobenzene SCHEMBL7157332 | 0.70 | ALDH1A1 (0.80) | ALDH1A1HSD17B10TDP1CYP3A4MAPK1 | |
| SCHEMBL1133769 | 0.69 | PGR (0.53) | ALDH1A1HSD17B10TDP1CYP3A4MAPK1 | |
| Sulfamide SCHEMBL19553940 | 0.69 | CA2 (0.46) | ALDH1A1HSD17B10TDP1CYP3A4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238401-B1 | SULFON AMIDES DERIVED FROM DIARYL METHANES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATION CONTAINING THEM | SANOFI (FR) | 1991-08-14 | — | — | EP | claimed |